Fine Structure Ventures is a Cambridge, Massachusetts based venture capital fund affiliated with FMR LLC, parent of Fidelity Investments. The firm partners with scientific and technical teams to support early-stage companies from pre-seed through pre-IPO, focusing on breakthroughs that transform research into market-ready solutions. The fund is managed by a team of scientists and investors who combine domain expertise and operational insight, ensuring each investment benefits from rigorous technical assessment and strategic guidance. It maintains board representation in more than 80 percent of its holdings and its portfolio includes upward of 300 active patents. Collective fundraising by portfolio companies tops $2 billion, reflecting its capacity to attract follow-on support and catalyze growth.
Investment activity spans biotechnology, aerospace, advanced materials, therapeutics, Internet of Things, robotics, artificial intelligence and energy. The firm collaborates closely with entrepreneurs to address technical challenges, scale operations and accelerate customer adoption. Advisory services are provided by Impresa Management LLC, with additional guidance from F-Prime since July 2024. Fine Structure Ventures emphasizes an active partnership model, often holding board seats and offering operational support to ensure that scientific advances translate into commercial success. Portfolio companies are evaluated on technical merit, team strength and the potential to reshape established processes.
Clean technology and battery science are major focus areas. The fund backs efforts in decarbonization, sustainable agriculture and manufacturing. Examples include Quaise’s geothermal drilling for baseload power; Ambient Photonics’ low-light photovoltaic cells; Boston Metal’s emissions-free steel via molten oxide electrolysis; Nitricity’s on-site sustainable fertilizer production; and Mantle’s waste-reducing metal 3D printing. In battery development, Fine Structure Ventures led the Series A round for Sepion Technologies, whose polymer materials boost energy density, cycle life and safety in lithium and lithium-metal batteries for longer-range electric vehicles and electric aviation.
